email@example.comGrowth, Development and Metabolism Programme
- Role of histone modification in fat cell differentiation.
- Role of microRNA in fat cell differentiation.
Sun, W., Xie, W., Xu, F., Grunstein, M. and Li, K.C. (2009) Dissecting nucleosome free regions by a segmental semi-Markov model. PLoS One. 4(3):e4721.
Xie, W., Song, C., Young, N.L., Sperling, A.S., Xu, F., Sridharan, R., Conway, A.E., Garcia, B.A., Plath, K., Clark, A.T. and Grunstein, M. (2009) Histone H3 lysine 56 acetylation is linked to the core transcriptional network in human embryonic stem cells. Molecular Cell. 33, 417-427.
Xu, F., Zhang, Q.Y., Zhang, K.L., Xie, W. and Grunstein, M. (2007) Sir2 Deacetylates Histone H3 Lysine 56 to Regulate Telomeric Heterochromatin Structure in Yeast. Molecular Cell.. 27, 890-900.
Millar, C.B., Xu, F., Zhang, K.L. and Grunstein, M. (2006) Acetylation of H2AZ Lys 14 is associated with genome-wide gene activity in yeast. Genes & Development. 20 (6), 711-722.
Xu, F., Zhang, K.L. and Grunstein, M. (2005) Acetylation in Histone H3 Globular Domain Regulates Gene Expression in Yeast. Cell. 121,375-385.
Yu, Y., Liu, Y., Shen, N., Xu, X., Xu, F., Jia, J., Jin, Y., Arnold, E. and Ding, J. (2004) Crystal structure of human tryptophanyl-tRNA synthetase catalytic fragment: insights into substrate recognition, tRNA binding, and angiogenesis activity. J Biol Chem. 279(9), 8378-8388.
Wang, Z.C., Wang, X.M., Jin, Y.X., Jiao, B.H., Xu, F., Miao, M.Y. and Zhu, K.J. Search for difference in aminoacylation of mitochondrial DNA-encoded wild-type and mutant human tRNALeu (UUR). (2003) IUBMB Life. 55(3), 139-144.
Xu, F., Jiang, G., Li, W., He, X., Jin, Y.X. and Wang, D. (2002) Three G.C base pairs required for the efficient aminoacylation of tRNATrp by tryptophanyl-tRNA synthetase from Bacillus subtilis. Biochemistry. 41(25), 8087-8092.
Jia, J., Xu, F., Chen, X., Chen, L., Jin, Y.X. and Wang, D.B. (2002) Two essential regions for tRNA recognition in Bacillus subtilis tryptophanyl-tRNA synthetase. Biochem J. 365(Pt 3), 749-756.
Xu, F., Chen, X.L., Xin, L., Chen, L., Jin, Y.X. and Wang, D.B. (2001) Species-Specific Differences in the Operational RNA Code for Aminoacylation of tRNATrp. Nucleic Acids Res. 29, 4125-4133.
Xu, F., Jia, J., Jin, Y.X. and Wang, D.B. (2001) High-Level expression and single-step purification of human tryptophanyl-tRNA synthetase. Protein Express. Purif. 23, 296-300.
Xu, R.H., Liu, J., Chen, X.W., Xu, F., Xie, Q., Yu, H., Guo, Q., Zhou, X.Q. and Jin, Y.X. (2001) Ribozyme-mediated Inhibition of Caspase-3 Activity Reduces Apoptosis Induced by 6-Hydroxydopamine in PC12 Cells. Brain Research. 899,10-19.
Senior Research Fellow
Sim Choon Kiat
Senior Research Officer
Senior Research Officer
Joanna Rajeswary Sinnakannu